A novel Protocol Ethics Tool Kit (‘Ethics Tool Kit’) has been developed by a multi-stakeholder group of the Multi-Regional Clinical Trials Center of Brigham and Women9s Hospital and Harvard. The purpose of the Ethics Tool Kit is to facilitate effective recognition, consideration and deliberation of critical ethical issues in clinical trial protocols. The Ethics Tool Kit may be used by investigators and sponsors to develop a dedicated Ethics Section within a protocol to improve the consistency and transparency between clinical trial (...) protocols and research ethics committee reviews. It may also streamline ethics review and may facilitate and expedite the review process by anticipating the concerns of ethics committee reviewers. Specific attention was given to issues arising in multinational settings. With the use of this Tool Kit, researchers have the opportunity to address critical research ethics issues proactively, potentially speeding the time and easing the process to final protocol approval. (shrink)

This is the first of two papers that use off-training set (OTS) error to investigate the assumption-free relationship between learning algorithms. This first paper discusses the senses in which there are no a priori distinctions between learning algorithms. (The second paper discusses the senses in which there are such distinctions.) In this first paper it is shown, loosely speaking, that for any two algorithms A and B, there are “as many” targets (or priors over targets) for which A has lower (...) expected OTS error than B as vice versa, for loss functions like zero-one loss. In particular, this is true if A is cross-validation and B is “anti-cross-validation” (choose the learning algorithm with largest cross-validation error). This paper ends with a discussion of the implications of these results for computational learning theory. It is shown that one cannot say: if empirical misclassification rate is low, the Vapnik-Chervonenkis dimension of your generalizer is small, and the training set is large, then with high probability your OTS error is small. Other implications for “membership queries” algorithms and “punting” algorithms are also discussed. (shrink)

The important recent book by Schurz ( 2019 ) appreciates that the no-free-lunch theorems (NFL) have major implications for the problem of (meta) induction. Here I review the NFL theorems, emphasizing that they do not only concern the case where there is a uniform prior—they prove that there are “as many priors” (loosely speaking) for which any induction algorithm _A_ out-generalizes some induction algorithm _B_ as vice-versa. Importantly though, in addition to the NFL theorems, there are many _free lunch_ theorems. (...) In particular, the NFL theorems can only be used to compare the expected performance of an induction algorithm _A_, considered in isolation, with the expected performance of an induction algorithm _B_, considered in isolation. There is a rich set of free lunches which instead concern the statistical _correlations_ among the generalization errors of induction algorithms. As I describe, the meta-induction algorithms that Schurz advocates as a “solution to Hume’s problem” are simply examples of such a free lunch based on correlations among the generalization errors of induction algorithms. I end by pointing out that the prior that Schurz advocates, which is uniform over bit frequencies rather than bit patterns, is contradicted by thousands of experiments in statistical physics and by the great success of the maximum entropy procedure in inductive inference. (shrink)

At least since Descartes, philosophers have been interested in the special knowledge or authority that we exhibit when we speak about our own thoughts, attitudes, and feelings. This book contends that even the best work in contemporary philosophy of mind fails to account for this sort of knowledge or authority because it does not pay the right sort of attention to the notion of expression. What's at stake is not only how to understand self-knowledge and first-person authority, but also what (...) it is that distinguishes conscious from unconscious psychological states, what the mental life of a nonlinguistic animal has in common with our sort of mental life, and how to think about Wittgenstein's legacy to the philosophy of mind. (shrink)

I criticize and emend J L Mackie's account of causal priority by replacing ‘fixity’ in its central clause by 'x is a causal condition of y, but y is not a causal condition of x'. This replacement works only if 'is a causal condition of' is not a symmetric relation. Even apart from our desire to account for causal priority, it is desirable to have an account of nonsymmetric conditionship. Truth, for example, is a condition of knowledge, but knowledge is (...) not a condition of truth. My definitions of 'sufficient condition for' and 'necessary condition for' do not imply that p is a sufficient condition of q if and only if q is a necessary condition of p. (shrink)

Rope Kojonen has presented a novel argument for design in biology by drawing on insights from evolutionary science. Without objecting to the explanatory role of evolution, he argues that there is further explanatory work to be done and that this is best achieved by an appeal to design. Here, I interpret his argument, and attempt to evaluate it, as a conjunctive explanation since he appeals to two explanations to account for the purposeful order and complexity of living organisms. Understood in (...) this way, I argue that he makes a very plausible case that two explanations (evolution and design) are better than one (evolution). I also explore the role that direct guidance by God might play in such an argument. (shrink)

In this collection of provocative essays, historians and literary theorists assess the influence of Michel Foucault, particularly his History of Sexuality, on the study of classics. Foucault's famous work presents a bold theory of sexuality for both ancient and modern times, and yet until now it has remained under-explored and insufficiently analyzed. By bringing together the historical knowledge, philological skills, and theoretical perspectives of a wide range of scholars, this collection enables the reader to explore Foucault's model of Greek culture (...) and see how well his interpretation accounts for the full range of evidence from Greece and Rome. Not only do the essays bring to light the assumptions, ideas, and practices that constituted the intimate lives of men and women in the ancient Mediterranean world, but they also demonstrate the importance of the History of Sexuality for fields as diverse as Greco-Roman antiquity, women's history, cultural studies, philosophy, and modern sexuality. The essays include "Situating The History of Sexuality" (the editors), "Taking the Sex Out of Sexuality: Foucault's Failed History" (Joel Black), "Incipit Philosophia" (Alain Vizier), "The Subject in Antiquity after Foucault" (Page duBois), "This Myth Which Is Not One: Construction of Discourse in Plato's Symposium" (Jeffrey S. Carnes), "Foucault's History of Sexuality: A Useful Theory for Women?" (Amy Richlin), "Catullan Consciousness, the 'Care of the Self,' and the Force of the Negative in History" (Paul Allen Miller), "Reversals of Platonic Love in Petronius' Satyricon" (Daniel B. McGlathery), and an essay from Dislocating Masculinity (Lin Foxhall). (shrink)

Explanatory models in psychiatry reflect what clinicians deem valuable in rendering people's behavior intelligible and thus help guide treatment choices for mental illnesses. This article outlines some key scientific and ethical principles of clinical explanation in twenty-first century psychiatry. Recent work in philosophy of science, clinical psychiatry, and psychiatric ethics are critically reviewed in order to elucidate conceptual underpinnings of contemporary explanatory models. Many explanatory models in psychiatry are reductionistic or eclectic. The former restrict options for diagnostic and therapeutic paradigm (...) choice, while the latter lack a well-defined theoretical basis. These two methodological approaches stand in a dialectical relation to one another insofar as clinicians often move from one approach to its antithesis, ultimately seeking a synthesis of the two approaches that satisfies clinical needs. Pragmatic considerations can help to transcend the reductionism/eclecticism dialectic. In the absence of a completed science of mental disorders, psychiatrists must tolerate ambiguity and uncertainty as they strive to integrate diverse explanatory concepts in a rigorous and evidence-based fashion. A pragmatic explanatory model in clinical psychiatry must focus on favorable treatment outcomes for patients by respecting the pluralistic, participatory, and provisional nature of psychiatric explanation. (shrink)

In Newcomb’s paradox you can choose to receive either the contents of a particular closed box, or the contents of both that closed box and another one. Before you choose though, an antagonist uses a prediction algorithm to accurately deduce your choice, and uses that deduction to fill the two boxes. The way they do this guarantees that you made the wrong choice. Newcomb’s paradox is that game theory’s expected utility and dominance principles appear to provide conflicting recommendations for what (...) you should choose. Here we show that the conflicting recommendations assume different probabilistic structures relating your choice and the algorithm’s prediction. This resolves the paradox: the reason there appears to be two conflicting recommendations is that the probabilistic structure relating the problem’s random variables is open to two, conflicting interpretations. We then show that the accuracy of the prediction algorithm in Newcomb’s paradox, the focus of much previous work, is irrelevant. We end by showing that Newcomb’s paradox is time-reversal invariant; both the paradox and its resolution are unchanged if the algorithm makes its ‘prediction’ after you make your choice rather than before. (shrink)

This article explores Mary Shelley’s Frankenstein as an “object of care” for use in examining the relationship between creativity and responsibility in the sciences and beyond. Through three short sketches from different disciplinary lenses—literature, science and technology studies, and feminist studies—readers get a sense of the different ways scholars might consider Shelley’s text as an object of care. Through an analysis and synthesis of these three sketches, the authors illustrate the value of such an object in thinking about broad cultural (...) issues. The article acts as a kind of boundary object by creating distinct, yet overlapping narratives from an object that is owned by many social worlds. The three sketches reveal Frankenstein as a thoughtful consideration about what it means to care for, or fail to care for, one’s creation, rather than as a cautionary tale about the evils of scientific hubris. Although infrastructures at universities often prevent interdisciplinary dialogue, the article concludes that purposeful boundary objects created around objects of care like Frankenstein can help build bridges and create shared meanings for new interdisciplinary spaces. (shrink)

How good is an explanation and when is one explanation better than another? In this paper, I address these questions by exploring probabilistic measures of explanatory power in order to defend a particular Bayesian account of explanatory goodness. Critical to this discussion is a distinction between weak and strong measures of explanatory power due to Good (Br J Philos Sci 19:123–143, 1968). In particular, I argue that if one is interested in the overall goodness of an explanation, an appropriate balance (...) needs to be struck between the weak explanatory power and the complexity of a hypothesis. In light of this, I provide a new defence of a strong measure proposed by Good by providing new derivations of it, comparing it with other measures and exploring its connection with information, confirmation and explanatory virtues. Furthermore, Good really presented a family of strong measures, whereas I draw on a complexity criterion that favours a specific measure and hence provides a more precise way to quantify explanatory goodness. (shrink)

Scholars and practitioners alike indicate a movement in corporate philanthropy toward “strategic” giving, for example, giving that improves the firm's strategic position (ultimately the “bottom line”) while it benefits the recipient of the philanthropic act. Although the existence of this trend is widely accepted, it is represented in the literature most often by anecdotal evidence. This article presents the findings of a survey of corporate giving managers of U.S. firms that have had an established giving program of at least 5 (...) years, with annual giving totaling at least $200,000 each year. The data show that corporate giving managers believe their firms are becoming increasingly strategic in their philanthropic activities. The findings also indicate that institutional-, firm-, and individual-level influences combine to precipitate strategic philanthropy. These findings lend support to the belief that the nature of corporate philanthropy is evolving to fit a more competitive marketplace. (shrink)

Naive mereology studies ordinary, common-sense beliefs about part and whole. Some of the speculations in this article on naive mereology do not bear directly on Peter van Inwagen's "Material Beings". The other topics, (1) and (2), both do. (1) Here is an example of Peter Unger's "Problem of the Many". How can a table be a collection of atoms when many collections of atoms have equally strong claims to be that table? Van Inwagen invokes fuzzy sets to solve this problem. (...) I claim that an alternative treatment of vagueness, supervaluations over many-value valuations, provides a better solution. (2) The Special Composition Question asks how parts compose a whole. One who rejects van Inwagen's answer in terms of constituting a life need not provide some alternative answer. Even if all answers to the Special Question fail, there are a multitude of less general composition questions that are not so difficult. (shrink)

Pragmatism is a distinctive approach to clinical research ethics that can guide bioethicists and members of institutional review boards (IRBs) as they struggle to balance the competing values of promoting medical research and protecting human subjects participating in it. After defining our understanding of pragmatism in the setting of clinical research ethics, we show how a pragmatic approach can provide guidance not only for the day-to-day functioning of the IRB, but also for evaluation of policy standards, such as the one (...) that addresses acceptable risks for healthy children in clinical research trials. We also show how pragmatic considerations might influence the debate about the use of deception in clinical research. Finally, we show how a pragmatic approach, by regarding the promotion of human research and the protection of human subjects as equally important values, helps to break down the false dichotomy between science and ethics in clinical research. (shrink)

In the form of inference known as inference to the best explanation there are various ways to characterise what is meant by the best explanation. This paper considers a number of such characterisations including several based on confirmation measures and several based on coherence measures. The goal is to find a measure which adequately captures what is meant by 'best' and which also yields the truth with a high degree of probability. Computer simulations are used to show that the overlap (...) coherence measure achieves this goal, enabling the true explanation to be identified almost as often as an approach which simply selects the most probable explanation. Further advantages to this approach are also considered in the case where there is uncertainty in the prior probability distribution. (shrink)

Everything red is colored, and all squares are polygons. A square is distinguished from other polygons by being four-sided, equilateral, and equiangular. What distinguishes red things from other colored things? This has been understood as a conceptual rather than scientific question. Theories of wavelengths and reflectance and sensory processing are not considered. Given just our ordinary understanding of color, it seems that what differentiates red from other colors is only redness itself. The Cambridge logician W. E. Johnson introduced the terms (...) determinate and determinable to apply to examples such as red and colored. Chapter XI, of Johnson's Logic, Part I (1921), “The Determinate and the Determinable,” is the main text for discussion of this distinction. (shrink)

Science fiction is often held up as a particularly philosophical genre. For, beyond actualising mind-experiment-like fantasies, science fiction films also commonly toy with speculative ideas, or else engineer encounters with the strange and unknown. Denis Villeneuve's Arrival is a contemporary science fiction film that does exactly this, by introducing Lovecraft-esque tentacular aliens whose arrival on Earth heralds in a novel, but ultimately paralysing, inhuman perspective on the nature of time and reality. This article shows how this cerebral film invites viewers (...) to confront a counterintuitive model of time that at once recalls and reposes what Gilles Deleuze called a “third synthesis” of time, and that which J. M. E. McTaggart named the a-temporal “C series” of “unreal” time. We finally suggest that Arrival's a-temporal conception of the future as having already happened can function as a key to understanding the fate of humanity as a whole as we pass from the anthropocene, in which humans have... (shrink)

This article argues for an aesthetic reading of to kalon, primarily as it appears in Aristotle’s Nicomachean Ethics. Aristotle uses to kalon to indicate that, to the morally serious, virtue is attractive and productive of a kind of pleasure. Read aesthetically, to kalon mitigates the tension between one’s own good and the common good. Aristotle shows how his students’ understanding of to kalon can be refined and thus preserved as an important and salutary feature of moral and political life.

A dualistic, discarnate picture haunts contemporary cognitive science of religion. Cognitive scientists of religion generally assert or assume a reductive physicalism, primarily through unconscious mental mechanisms that detect supernatural agency where none exists and a larger purpose to life when none exists. Accompanying this focus is a downplaying of conscious reflection in religious belief and practice. Yet the mind side of dualism enters into CSR in interesting ways. Some cognitive scientists turn practitioners of religion into dualists who allegedly believe in (...) disembodied spirits. By emphasizing supernatural agency, CSR neglects nonpersonal powers and meanings in religion, both in terms of magical thinking and practice and of nonpersonal conceptions of divinity. Additionally, some cognitive scientists of religion declare that all humans are innate dualists. They use this alleged dualism to explain beliefs about both an afterlife and transfers of consciousness. Finally, some call on this dualism to serve a salvific function, trying to salvage some meaning to human life. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:War, Peace, and Reconciliation: A Theological Inquiry by Theodore R. WeberDavid H. MessnerWar, Peace, and Reconciliation: A Theological Inquiry Theodore R. Weber EUGENE, OR: WIPF & STOCK, 2015. 182 pp. $23.00Weber's book makes a helpful contribution to enlivening more theologically grounded strategies for peacemaking through reconciliation. It is a careful, systematic work that takes as its foundation a distinctively Christian view of [End Page 214] God's nature and (...) relation to the world. As a scholar and a pastor for over fifty years, Weber brings a much-needed, wise, and re-centered view to the questions entangled in war, peace, and reconciliation. He advises us not to look first into the realities of war for God, but to look to understand God as the context for all human conflict. He forcefully calls the reader to be a reconciler despite the intractability of conflict. The book is structured in three main parts, beginning with the theological context, then the political context, and, last, to peace, justice, and the church.The "war" that Weber addresses is interstate conflict, representing the negation of the web of relationships constituting a healthy international system. War disrupts God's plan and ruptures the right relationship between humanity and God (43–44). Throughout, Weber embraces a kind of Christian Realism, one that takes seriously the loving nature of God, the sinfulness of humanity, and the limits and possibilities for peacemaking in a human world. Downplaying the pacifistic message of Jesus, Weber highlights the necessities within a fallen world. We cannot eliminate war as a category of existence under the conditions of sin (until the eschaton), but with right orientation and action we can eliminate some war.Noting inadequacies of the just war tradition (though not dispensing with it), Weber identifies the need to ground it more firmly in theology, including enhanced attention to "just intention" as a primary criterion in evaluating the prosecution of war, displacing cause as the first question with which we must interrogate ourselves. Discernment about war and peace must be an ongoing conversation that should include people of faith as well as policymakers. Weber's theological and pastoral sensibilities, alongside his political savvy throughout, make the book a pleasurable and provocative read.The definition of reconciliation deployed is broad and complex, and Weber marshals it for powerful work. Reconciliation "is God's work—the movement of Divine grace through history, engaging all aspects of brokenness and promise and reaching its climax of fulfillment and disclosure in the life, death, and resurrection of Jesus Christ" (3). Grace continually calls humanity to enter into the work of reconciliation. Here Weber introduces the idea of relational power; more nuanced than mere substantive power, it connects to the core idea of institution building and the critical emphasis on strengthening the social fabric in the interest of peace. It is the hallmark of the reconciling transformation from systems of dominance to relationships of consent.The book raises questions regarding how to put reconciliation as described into concrete practice, responding to real cases and controversies. Also, there could be added discussion, against this theological backdrop, of what opportunities exist amid current US and global regime change to enter this reconciling activity more fully.Ultimately, the Christian context is central to understanding the ethics that Weber advances. Weber recommends a biblical foundation, one in which [End Page 215] we take the benefit of reading scripture backward from the Christ event. Such an exegetical strategy reveals that God has a plan for all of humanity, a vision of inclusiveness and reconciliation. It is from this vantage point of God's culminating vision, Weber illuminates, that we can understand and embrace human action throughout history and the meaningful, if incomplete, work of reconciliation to which we must commit ourselves, both politically and spiritually. [End Page 216]David H. MessnerEmory UniversityCopyright © 2018 Society of Christian Ethics... (shrink)

This article answers John Biro's "Knowability, Believability, and Begging the Question: a Reply to Sanford" in "Metaphilosophy" 15 (1984). Biro and I agree that of two argument instances with the same form and content, one but not the other can beg the question, depending on other factors. These factors include actual beliefs, or so I maintain (against Biro) with the help of some analysed examples. Brief selections from Archbishop Whatley and J S Mill suggest that they also regard reference to (...) actual beliefs as essential to explaining begging the question. (shrink)

Book reviewed in this article: Suffering and the Beneficent Community: Beyond Libertarianism. By Erich H. Loewy. The Nature of Suffering and the Goals of Medicine. By Eric J. Cassell.

There are four types of information an agent can have concerning the state of the universe: information acquired via observation, via control, via prediction, or via retrodiction, i.e., memory. Each of these four types of information appear to rely on a different kind of physical device. However it turns out that there is some mathematical structure that is common to those four types of devices. Any device that possesses that structure is known as an “inference device”. Here I review some (...) of the properties of IDs, including their relation with Turing machines, and quantum mechanics. I also review the bounds on the joint information about the physical universe that can be held by any set of IDs. These bounds constrain the possible mathematical structure of any universe that contains agents with information concerning that universe in which they are embedded. (shrink)

Philosophy in the 19th century experienced a ‘turn from idealism,’ when idealist philosophies were largely abandoned for materialist ones. Scientific naturalism is now considered by many analytic philosophers to be the new orthodoxy, largely in part due to the success of the scientific method. The New Atheists, such as Daniel Dennett and Richard Dawkins, claim it is Darwin in particular who deserves much of the credit for repudiating the traditional Mind-first world view. Some, like Alvin Plantinga and Michael Behe, maintain (...) the opposite, that evolution casts doubt on naturalism and supports theism. This dissertation seeks to determine just what exactly the logical implications of evolutionary theory are. Is evolution incompatible with theism? Does the acceptance of evolution necessarily entail naturalism and preclude theism? Is it possible, as naturalism maintains, that everything can be reduced to physical processes, or are there too many recalcitrant phenomena that defy reduction? Answering these involves a detailed analysis of the concepts, ‘evolution,’ ‘naturalism,’ and ‘theism.’ Just what exactly does accepting evolutionary theory entail? How is it different from Darwinism? Is evolution guided or unguided? What is naturalism? There are many different types of metaphysical naturalists: eliminative materialists, physicalists, and emergent property dualists. What is the relationship between metaphysical naturalism and methodological naturalism? Theism affirms a creator God who sustains all being, who is transcendent and yet immanent. So if theism posits a God who is active in the world, does this mean that scientific investigation may at times have to admit supernatural explanations when natural ones fail? My general conclusion is a type of mitigated skepticism – that given evolution, neither naturalism nor theism logically follows. As to whether evolution is guided or unguided, the only correct position is ‘undetermined.’ In this instance metaphysical positions may fill in the gaps in knowledge by projection, but cannot fulfill the necessary and sufficient conditions required for knowledge. Metaphysical naturalism and theism are worldviews that an individual adopts as the most overall coherent explanation of the wide variety of experiences, intuitions, and reflections on their life. Whether evolution offers evidence for one and against the other is often based upon one’s prior metaphysical assumptions, since all facts are theory laden. The underdetermination of theory allows for multiple theories to cover the same phenomena, with each offering an epistemically adequate explanation. However, numerous recalcitrant anomalies which defy scientific explanation and reduction present problems for the strict naturalist. While neither naturalism nor theism can be determined to be objectively true, one can offer reasons for choosing one or the other on the basis of overall coherence. (shrink)

This paper provides a new approach to inference to the best explanation based on a new coherence measure for comparing how well hypotheses explain the evidence. It addresses a number of criticisms of the use of probabilistic measures in this context by Clark Glymour, including limitations of earlier work on IBE. Computer experiments are used to show that the new approach finds the truth with a high degree of accuracy in hypothesis selection tasks and that in some cases its accuracy (...) is greater than hypothesis selection based on maximizing posterior probability. Hence, by overcoming some of the problems with the previous approach, this work provides a more adequate defence of IBE and suggests that IBE not only tracks truth but also has practical advantages over the previous approach. Applications of the new approach to parameter estimation and model selection are also explored. (shrink)

A semantics of vagueness should reject the principle that every statement has a truth-value yet retain the classical tautologies. A many-value, non-truth-functional semantics and a semantics of super-valuations each have this result. According to the super-valuation approach, 'if a man with n hairs on his head is bald, then a man with n plus one hairs on his head is also bald' is false because it comes out false no matter how the vague predicate 'is bald' is appropriately made precise. (...) But why should a sentence in which components actually remain imprecise be regarded as actually false just because it would be false if its components were precise? On one of the alternative treatments of quantification allowed by the many-value approach, the sentence in question is assigned an intermediate value closer to 'false' than to 'true'. Despite the elegance of the super-valuation approach, there are reasons to prefer the many-value approach. (shrink)

We introduce a framework that can be used to model both mathematics and human reasoning about mathematics. This framework involves stochastic mathematical systems (SMSs), which are stochastic processes that generate pairs of questions and associated answers (with no explicit referents). We use the SMS framework to define normative conditions for mathematical reasoning, by defining a “calibration” relation between a pair of SMSs. The first SMS is the human reasoner, and the second is an “oracle” SMS that can be interpreted as (...) deciding whether the question–answer pairs of the reasoner SMS are valid. To ground thinking, we understand the answers to questions given by this oracle to be the answers that would be given by an SMS representing the entire mathematical community in the infinite long run of the process of asking and answering questions. We then introduce a slight extension of SMSs to allow us to model both the physical universe and human reasoning about the physical universe. We then define a slightly different calibration relation appropriate for the case of scientific reasoning. In this case the first SMS represents a human scientist predicting the outcome of future experiments, while the second SMS represents the physical universe in which the scientist is embedded, with the question–answer pairs of that SMS being specifications of the experiments that will occur and the outcome of those experiments, respectively. Next we derive conditions justifying two important patterns of inference in both mathematical and scientific reasoning: (i) the practice of increasing one’s degree of belief in a claim as one observes increasingly many lines of evidence for that claim, and (ii) abduction, the practice of inferring a claim’s probability of being correct from its explanatory power with respect to some other claim that is already taken to hold for independent reasons. (shrink)

We present a conceptual framework on the experience of time and provide a coherent basis on which to base further inquiries into qualitative approaches concerning time experience. We propose two Time-Layers and two Time-Formats forming four Time-Domains. Micro-Flow and Micro-Structure represent the implicit phenomenal basis, from which the explicit experiences of Macro-Flow and Macro-Structure emerge. Complementary to this theoretical proposal, we present empirical results from qualitative content analysis obtained from 25 healthy participants. The data essentially corroborate the theoretical proposal. With (...) respect to Flow, the phenomenally accessible time experience appeared as a continuous passage reaching from the past through the present into the future. With respect to Structure, the individual present was embedded in the individual biography, emerging from past experiences and comprising individual plans and goals. New or changing plans and goals were being integrated into the existing present, thus forming a new present. The future appeared as changeable within the present, by means from the past, and therefore as a space of potential opportunities. Exemplarily, we discuss these results in relation to previous empirical findings on deviant experiences of time in Autism Spectrum Disorder that is presumably characterized by a breakdown of Flow and concomitant compensatory repetition resulting in an overly structured time. Finally, we speculate about possible implications of these findings both for psychopathological and neuroscientific research. (shrink)

Based on Medicine as a human experience / David E. Reiser, David H. Rosen. c1984.

This study takes a Christian perspective on the entire Bible, rather than simply the New Testament. David Wenkel asks: Why did Jesus have to be beaten before his death on the cross? Christian theology has largely focused on Jesus' death but has given relatively little attention to his sufferings. Wenkel's answer contextualizes Jesus' crucifixion sufferings as informed by the language of Proverbs. He explains that Jesus' sufferings demonstrate the wisdom of God's plan to provide a substitute for foolish sinners. (...) Jesus was beaten as a fool - even though he was no fool, in order to fulfill God's loving plan of salvation. This analysis is then placed within the larger storyline of the whole bible - from the Garden of Eden to the story of Israel and beyond. (shrink)

This paper considers an application of work on probabilistic measures of coherence to inference to the best explanation. Rather than considering information reported from different sources, as is usually the case when discussing coherence measures, the approach adopted here is to use a coherence measure to rank competing explanations in terms of their coherence with a piece of evidence. By adopting such an approach IBE can be made more precise and so a major objection to this mode of reasoning can (...) be addressed. Advantages of the coherence - based approach are pointed out by comparing it with several other ways to characterize ‘ best explanation ’ and showing that it takes into account their insights while overcoming some of their problems. The consequences of adopting this approach for IBE are discussed in the context of recent discussions about the relationship between IBE and Bayesianism. (shrink)

From an ethical point of view, shared decision-making is preferable to either physician paternalism or patient sovereignty. The traditional model of doctor-patient communication is too directive and too unconcerned with the patient's values to support truly shared decision-making. The traditional distinction between rhetoric and sophistic can provide the basis for a new model of mutual persuasion that does not limit communication to information, and that avoids the spectre of manipulation.

The epistemic arrow of time is the fact that our knowledge of the past seems to be both of a different kind and more detailed than our knowledge of the future. Just like with the other arrows of time, it has often been speculated that the epistemic arrow arises due to the second law of thermodynamics. In this paper, we investigate the epistemic arrow of time using a fully formal framework. We begin by defining a memory system as any physical (...) system whose present state can provide information about the state of the external world at some time other than the present. We then identify two types of memory systems in our universe, along with an important special case of the first type, which we distinguish as a third type of memory system. We show that two of these types of memory systems are time-symmetric, able to provide knowledge about both the past and the future. However, the third type of memory systems exploits the second law of thermodynamics, at least in all of its instances in our universe that we are aware of. The result is that in our universe, this type of memory system only ever provides information about the past. We also argue that human memory is of this third type, completing the argument. We end by scrutinizing the basis of the second law itself. This uncovers a previously unappreciated formal problem for common arguments that try to derive the second law from the “Past Hypothesis”, i.e., from the claim that the very early universe was in a state of extremely low entropy. Our analysis is indebted to prior work by one of us but expands and improves upon this work in several respects. (shrink)

Two of the probabilistic measures of coherence discussed in this paper take probabilistic dependence into account and so depend on prior probabilities in a fundamental way. An example is given which suggests that this prior-dependence can lead to potential problems. Another coherence measure is shown to be independent of prior probabilities in a clearly defined sense and consequently is able to avoid such problems. The issue of prior-dependence is linked to the fact that the first two measures can be understood (...) as measures of coherence as striking agreement, while the third measure represents coherence as agreement. Thus, prior (in)dependence can be used to distinguish different conceptions of coherence. (shrink)